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Quantification of mRNA cap-modifications by means of LC-QqQ-MS

Enzymatic modification of the 5′-cap is a versatile approach to modulate the properties of mRNAs. Transfer of methyl groups from S-adenosyl-l-methionine (AdoMet) or functional moieties from non-natural analogs by methyltransferases (MTases) allows for site-specific modifications at the cap. These mo...

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Detalles Bibliográficos
Autores principales:	Muthmann, Nils, Špaček, Petr, Reichert, Dennis, van Dülmen, Melissa, Rentmeister, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612805/ https://www.ncbi.nlm.nih.gov/pubmed/34058305 http://dx.doi.org/10.1016/j.ymeth.2021.05.018

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