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Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans

Athletic performance relies on tendons, which enable movement by transferring forces from muscles to the skeleton. Yet how load-bearing structures in tendon sense and adapt to physical demands is not understood. Here, by performing calcium (Ca(2+)) imaging in mechanically loaded tendon explants from...

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Detalles Bibliográficos
Autores principales:	Passini, Fabian S., Jaeger, Patrick K., Saab, Aiman S., Hanlon, Shawn, Chittim, Nicole A., Arlt, Matthias J., Ferrari, Kim David, Haenni, Dominik, Caprara, Sebastiano, Bollhalder, Maja, Niederöst, Barbara, Horvath, Aron N., Götschi, Tobias, Ma, Shang, Passini-Tall, Bettina, Fucentese, Sandro F., Blache, Ulrich, Silván, Unai, Weber, Bruno, Silbernagel, Karin Grävare, Snedeker, Jess G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612848/ https://www.ncbi.nlm.nih.gov/pubmed/34031557 http://dx.doi.org/10.1038/s41551-021-00716-x

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