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Embodying an artificial hand increases blood flow to the investigated limb

Background: The autonomic nervous system is the main determinant of the blood flow directed towards a body part, and it is tightly connected to the representation of the body in the brain; would the experimental modulation of the sense of limb ownership affect its blood perfusion? Methods: In health...

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Autores principales: Di Pino, Giovanni, Mioli, Alessandro, Altamura, Claudia, D'Alonzo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612882/
https://www.ncbi.nlm.nih.gov/pubmed/35747768
http://dx.doi.org/10.12688/openreseurope.13641.3
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author Di Pino, Giovanni
Mioli, Alessandro
Altamura, Claudia
D'Alonzo, Marco
author_facet Di Pino, Giovanni
Mioli, Alessandro
Altamura, Claudia
D'Alonzo, Marco
author_sort Di Pino, Giovanni
collection PubMed
description Background: The autonomic nervous system is the main determinant of the blood flow directed towards a body part, and it is tightly connected to the representation of the body in the brain; would the experimental modulation of the sense of limb ownership affect its blood perfusion? Methods: In healthy participants, we employed the rubber hand illusion paradigm to modulate limb ownership while we monitored the brachial artery blood flow and resistance index within the investigated limb. Results: In all conditions with brush-stroking, we found an initial drop in the blood flow due to tactile stimulation. Subsequently, in the illusion condition (where both the rubber and real hand synchronous brush-stroking were present), the blood flow rose significantly faster and reached significantly higher values. Moreover, the increase in blood flow correlated with the extent of embodiment as measured by questionnaires and correlated negatively with the change of peripherical vascular resistance. Conclusions: These findings suggest that modulating the representation of a body part impacts its blood perfusion.
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spelling pubmed-76128822022-06-22 Embodying an artificial hand increases blood flow to the investigated limb Di Pino, Giovanni Mioli, Alessandro Altamura, Claudia D'Alonzo, Marco Open Res Eur Research Article Background: The autonomic nervous system is the main determinant of the blood flow directed towards a body part, and it is tightly connected to the representation of the body in the brain; would the experimental modulation of the sense of limb ownership affect its blood perfusion? Methods: In healthy participants, we employed the rubber hand illusion paradigm to modulate limb ownership while we monitored the brachial artery blood flow and resistance index within the investigated limb. Results: In all conditions with brush-stroking, we found an initial drop in the blood flow due to tactile stimulation. Subsequently, in the illusion condition (where both the rubber and real hand synchronous brush-stroking were present), the blood flow rose significantly faster and reached significantly higher values. Moreover, the increase in blood flow correlated with the extent of embodiment as measured by questionnaires and correlated negatively with the change of peripherical vascular resistance. Conclusions: These findings suggest that modulating the representation of a body part impacts its blood perfusion. F1000 Research Limited 2022-04-21 /pmc/articles/PMC7612882/ /pubmed/35747768 http://dx.doi.org/10.12688/openreseurope.13641.3 Text en Copyright: © 2022 Di Pino G et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Di Pino, Giovanni
Mioli, Alessandro
Altamura, Claudia
D'Alonzo, Marco
Embodying an artificial hand increases blood flow to the investigated limb
title Embodying an artificial hand increases blood flow to the investigated limb
title_full Embodying an artificial hand increases blood flow to the investigated limb
title_fullStr Embodying an artificial hand increases blood flow to the investigated limb
title_full_unstemmed Embodying an artificial hand increases blood flow to the investigated limb
title_short Embodying an artificial hand increases blood flow to the investigated limb
title_sort embodying an artificial hand increases blood flow to the investigated limb
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612882/
https://www.ncbi.nlm.nih.gov/pubmed/35747768
http://dx.doi.org/10.12688/openreseurope.13641.3
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