Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells

B cell responses are critical for antiviral immunity. However, a comprehensive picture of antigen-specific B cell differentiation, clonal proliferation, and dynamics in different organs after infection is lacking. Here, by combining single-cell RNA and B cell receptor (BCR) sequencing of antigen-spe...

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Detalles Bibliográficos
Autores principales: Mathew, Nimitha R., Jayanthan, Jayalal K., Smirnov, Ilya V., Robinson, Jonathan L., Axelsson, Hannes, Nakka, Sravya S., Emmanouilidi, Aikaterini, Czarnewski, Paulo, Yewdell, William T., Schön, Karin, Lebrero-Fernández, Cristina, Bernasconi, Valentina, Rodin, William, Harandi, Ali M., Lycke, Nils, Borcherding, Nicholas, Yewdell, Jonathan W., Greiff, Victor, Bemark, Mats, Angeletti, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612943/
https://www.ncbi.nlm.nih.gov/pubmed/34161770
http://dx.doi.org/10.1016/j.celrep.2021.109286

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