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The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma

PURPOSE: Ovarian high-grade serous carcinoma (HGSC) is usually diagnosed at late stage. We investigated whether late-stage HGSC has unique genomic characteristics consistent with acquisition of evolutionary advantage compared with early-stage tumors. EXPERIMENTAL DESIGN: We performed targeted next-g...

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Detalles Bibliográficos
Autores principales: Cheng, Zhao, Mirza, Hasan, Ennis, Darren P., Smith, Philip, Morrill Gavarró, Lena, Sokota, Chishimba, Giannone, Gaia, Goranova, Theodora, Bradley, Thomas, Piskorz, Anna, Lockley, Michelle, Kaur, Baljeet, Singh, Naveena, Tookman, Laura A., Krell, Jonathan, McDermott, Jacqueline, Macintyre, Geoffrey, Markowetz, Florian, Brenton, James D., McNeish, Iain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612959/
https://www.ncbi.nlm.nih.gov/pubmed/35398881
http://dx.doi.org/10.1158/1078-0432.CCR-21-1643