Cargando…

A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era

OBJECTIVES: Fluid bolus resuscitation in African children is harmful. Little research has evaluated physiologic effects of maintenance-only fluid strategy. DESIGN: We describe the efficacy of fluid-conservative resuscitation of septic shock using case-fatality, hemodynamic, and myocardial function e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Obonyo, Nchafatso G., Olupot-Olupot, Peter, Mpoya, Ayub, Nteziyaremye, Julius, Chebet, Martin, Uyoga, Sophie, Muhindo, Rita, Fanning, Jonathon P., Shiino, Kenji, Chan, Jonathan, Fraser, John F., Maitland, Kathryn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613033/ https://www.ncbi.nlm.nih.gov/pubmed/35446796 http://dx.doi.org/10.1097/PCC.0000000000002968

Ejemplares similares

Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration
por: Houston, Kirsty A., et al.
Publicado: (2019)

Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)
por: Obonyo, Nchafatso, et al.
Publicado: (2017)

Assessment of Myocardial Function and Injury by Echocardiography and Cardiac Biomarkers in African Children With Severe Plasmodium falciparum Malaria*
por: Kotlyar, Simon, et al.
Publicado: (2018)

The clinical spectrum of severe childhood malaria in Eastern Uganda
por: Olupot-Olupot, Peter, et al.
Publicado: (2020)

Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration
por: Houston, Kirsty A., et al.
Publicado: (2017)

Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia
por: Olupot-Olupot, Peter, et al.
Publicado: (2014)

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol
por: Olupot-Olupot, Peter, et al.
Publicado: (2021)

Perspectives on aetiology, pathophysiology and management of shock in African children
por: Nteziyaremye, Julius, et al.
Publicado: (2017)

Evaluation of the diagnostic accuracy and cost of different methods for the assessment of severe anaemia in hospitalised children in Eastern Uganda
por: Olupot-Olupot, Peter, et al.
Publicado: (2019)

High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda
por: Olupot-Olupot, Peter, et al.
Publicado: (2017)

Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial
por: Olupot-Olupot, Peter, et al.
Publicado: (2023)

High false discovery rate of the Architect anti‐HCV screening test in blood donors in Uganda and evaluation of an algorithm for confirmatory testing
por: Lucey, Olivia, et al.
Publicado: (2022)

Modifying gut integrity and microbiome in children with severe acute malnutrition using legume-based feeds (MIMBLE): A pilot trial
por: Calder, Nuala, et al.
Publicado: (2021)

Modifying Intestinal Integrity and Micro Biome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial
por: Walsh, Kevin, et al.
Publicado: (2018)

Cardiovascular abnormalities in chest radiographs of children with pneumonia, Uganda
por: Nabawanuka, Eva, et al.
Publicado: (2023)

Point-of-care haemoglobin testing in African hospitals: a neglected essential diagnostic test
por: Uyoga, Sophie, et al.
Publicado: (2021)

Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial
por: Maitland, Kathryn, et al.
Publicado: (2013)

Mortality risk over time after early fluid resuscitation in African children
por: George, Elizabeth C., et al.
Publicado: (2019)

Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study
por: Brent, Bernadette, et al.
Publicado: (2019)

Children’s Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia
por: Maitland, Kathryn, et al.
Publicado: (2018)

Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub‐Saharan Africa
por: Uyoga, Sophie, et al.
Publicado: (2019)

Healthcare-provider perceptions of barriers to oxygen therapy for paediatric patients in three government-funded eastern Ugandan hospitals; a qualitative study
por: Dauncey, Jonathan W., et al.
Publicado: (2019)

Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review
por: Obonyo, Nchafatso G., et al.
Publicado: (2016)

Endotoxaemia is common in children with Plasmodium falciparum malaria
por: Olupot-Olupot, Peter, et al.
Publicado: (2013)

Incidence and predictors of hospital readmission in children presenting with severe anaemia in Uganda and Malawi: a secondary analysis of TRACT trial data
por: Connon, Roisin, et al.
Publicado: (2021)

‘The Words Will Pass with the Blowing Wind’: Staff and Parent Views of the Deferred Consent Process, with Prior Assent, Used in an Emergency Fluids Trial in Two African Hospitals
por: Molyneux, Sassy, et al.
Publicado: (2013)

A predictive algorithm for identifying children with sickle cell anemia among children admitted to hospital with severe anemia in Africa
por: Olupot‐Olupot, Peter, et al.
Publicado: (2022)

Informing thresholds for paediatric transfusion in Africa: the need for a trial
por: Maitland, Kathryn, et al.
Publicado: (2019)

Sickle cell anaemia and severe Plasmodium falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT)
por: Uyoga, Sophie, et al.
Publicado: (2022)

Bacterial Aetiology and Antibiotic Susceptibility Profile of Post-Operative Sepsis among Surgical Patients in a Tertiary Hospital in Rural Eastern Uganda
por: George, Masifa, et al.
Publicado: (2018)

Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial
por: Maitland, Kathryn, et al.
Publicado: (2019)

Increased adhesion of Plasmodium falciparum infected erythrocytes to ICAM-1 in children with acute intestinal injury
por: Church, James A., et al.
Publicado: (2016)

Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial
por: Mpoya, Ayub, et al.
Publicado: (2015)

Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation
por: Fanning, Jonathon P., et al.
Publicado: (2021)

Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score
por: George, Elizabeth C., et al.
Publicado: (2015)

Microvascular dysfunction in septic and dengue shock: Pathophysiology and implications for clinical management
por: McBride, Angela, et al.
Publicado: (2020)

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis
por: Obonyo, Nchafatso G., et al.
Publicado: (2023)

Unusual clinical spectra of childhood severe malaria during malaria epidemic in eastern Uganda: a prospective study
por: Namayanja, Cate, et al.
Publicado: (2023)

Where have all the children gone? High HIV prevalence in infants attending nutrition and inpatient entry points
por: Kiyaga, Charles, et al.
Publicado: (2018)

PARIST study protocol: a phase I/II randomised, controlled clinical trial to assess the feasibility, safety and effectiveness of paracetamol in resolving acute kidney injury in children with severe malaria
por: Paasi, George, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0irk52addeodt22e8dt7giiqjo