Cargando…

Targeting Viral cccDNA for Cure of Chronic Hepatitis B

PURPOSE OF REVIEW: Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), is a major cause of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. HBV replication is characterized by the synthesis of covalently closed circular (ccc) DNA which is not targeted by antiviral nucle...

Descripción completa

Detalles Bibliográficos
Autores principales: Ligat, Gaëtan, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613435/
https://www.ncbi.nlm.nih.gov/pubmed/36034467
http://dx.doi.org/10.1007/s11901-020-00534-w