Cargando…
Targeting Viral cccDNA for Cure of Chronic Hepatitis B
PURPOSE OF REVIEW: Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), is a major cause of advanced liver disease and hepatocellular carcinoma (HCC) worldwide. HBV replication is characterized by the synthesis of covalently closed circular (ccc) DNA which is not targeted by antiviral nucle...
Autores principales: | Ligat, Gaëtan, Goto, Kaku, Verrier, Eloi, Baumert, Thomas F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613435/ https://www.ncbi.nlm.nih.gov/pubmed/36034467 http://dx.doi.org/10.1007/s11901-020-00534-w |
Ejemplares similares
-
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target
por: Verrier, Eloi R, et al.
Publicado: (2023) -
Hepatitis B virus–host interactions and novel targets for viral cure
por: Ligat, Gaëtan, et al.
Publicado: (2021) -
cccDNA Maintenance in Chronic Hepatitis B – Targeting the Matrix of Viral Replication
por: Dandri, Maura, et al.
Publicado: (2020) -
Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs
por: Li, Feng, et al.
Publicado: (2016) -
Mechanism of Hepatitis B Virus cccDNA Formation
por: Wei, Lei, et al.
Publicado: (2021)