Cargando…
Water contact angle is not a good predictor of biological responses to materials
Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging f...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613460/ https://www.ncbi.nlm.nih.gov/pubmed/28683556 http://dx.doi.org/10.1116/1.4989843 |
_version_ | 1783605483985174528 |
---|---|
author | Alexander, Morgan R. Williams, Paul |
author_facet | Alexander, Morgan R. Williams, Paul |
author_sort | Alexander, Morgan R. |
collection | PubMed |
description | Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging from their work that has failed to find relationships between WCA and microbial and stem cell attachment within large diversity material libraries and compare with the literature concluding that such simple rules are (unfortunately) wholly inadequate to explain cell–material interactions. |
format | Online Article Text |
id | pubmed-7613460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
record_format | MEDLINE/PubMed |
spelling | pubmed-76134602022-08-29 Water contact angle is not a good predictor of biological responses to materials Alexander, Morgan R. Williams, Paul Biointerphases Article Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging from their work that has failed to find relationships between WCA and microbial and stem cell attachment within large diversity material libraries and compare with the literature concluding that such simple rules are (unfortunately) wholly inadequate to explain cell–material interactions. 2017-07-06 2017-07-06 /pmc/articles/PMC7613460/ /pubmed/28683556 http://dx.doi.org/10.1116/1.4989843 Text en https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Article Alexander, Morgan R. Williams, Paul Water contact angle is not a good predictor of biological responses to materials |
title | Water contact angle is not a good predictor of biological responses to materials |
title_full | Water contact angle is not a good predictor of biological responses to materials |
title_fullStr | Water contact angle is not a good predictor of biological responses to materials |
title_full_unstemmed | Water contact angle is not a good predictor of biological responses to materials |
title_short | Water contact angle is not a good predictor of biological responses to materials |
title_sort | water contact angle is not a good predictor of biological responses to materials |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613460/ https://www.ncbi.nlm.nih.gov/pubmed/28683556 http://dx.doi.org/10.1116/1.4989843 |
work_keys_str_mv | AT alexandermorganr watercontactangleisnotagoodpredictorofbiologicalresponsestomaterials AT williamspaul watercontactangleisnotagoodpredictorofbiologicalresponsestomaterials |