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NLRP3 Inflammasome Priming and Activation Are Regulated by a Phosphatidylinositol-Dependent Mechanism

Imbalance in lipid homeostasis is associated with discrepancies in immune signaling and is tightly linked to metabolic disorders. The diverse ways in which lipids impact immune signaling, however, remain ambiguous. The phospholipid phosphatidylinositol (PI), which is implicated in numerous immune di...

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Detalles Bibliográficos
Autores principales: Hamilton, Claire, Olona, Antoni, Leishman, Stuart, MacDonald-Ramsahai, Kelly, Cockcroft, Shamshad, Larrouy-Maumus, Gerald, Anand, Paras K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613559/
https://www.ncbi.nlm.nih.gov/pubmed/36038196
http://dx.doi.org/10.4049/immunohorizons.2200058

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