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The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A

BACKGROUND AND AIMS: High lipoprotein(a) [Lp(a)] concentrations are associated with increased coronary artery disease (CAD) risk. Lp(a) is regulated mainly genetically by the LPA gene but involved genetic variants have not been fully elucidated. Improved understanding of the entanglements of genetic...

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Detalles Bibliográficos
Autores principales: Grüneis, Rebecca, Lamina, Claudia, Di Maio, Silvia, Schönherr, Sebastian, Zoescher, Peter, Forer, Lukas, Streiter, Gertraud, Peters, Annette, Gieger, Christian, Köttgen, Anna, Kronenberg, Florian, Coassin, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613586/
https://www.ncbi.nlm.nih.gov/pubmed/35534298
http://dx.doi.org/10.1016/j.atherosclerosis.2022.04.023