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A hydro-thermophoretic trap for microparticles near a gold-coated substrate†
Optical tweezers have revolutionised micromanipulation from physics and biology to material science. However, the high laser power involved in optical trapping can damage biological samples. In this context, indirect trapping of microparticles and objects using fluid flow fields has assumed great im...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613615/ https://www.ncbi.nlm.nih.gov/pubmed/36040245 http://dx.doi.org/10.1039/d2sm00627h |
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author | Nalupurackal, Gokul Gunaseelan, M. Roy, Srestha Lokesh, Muruga Kumar, Sumeet Vaippully, Rahul Singh, Rajesh Roy, Basudev |
author_facet | Nalupurackal, Gokul Gunaseelan, M. Roy, Srestha Lokesh, Muruga Kumar, Sumeet Vaippully, Rahul Singh, Rajesh Roy, Basudev |
author_sort | Nalupurackal, Gokul |
collection | PubMed |
description | Optical tweezers have revolutionised micromanipulation from physics and biology to material science. However, the high laser power involved in optical trapping can damage biological samples. In this context, indirect trapping of microparticles and objects using fluid flow fields has assumed great importance. It has recently been shown that cells and particles can be turned in the pitch sense by opto-plasmonic heating of a gold surface constituting one side of a sample chamber. We extend that work to place two such hotspots in close proximity to each other to form a very unique configuration of flow fields forming an effective quasi-three-dimensional ‘trap’, assisted by thermophoresis. This is effectively a harmonic trap confining particles in all three dimensions without relying on other factors to confine the particles close to the surface. We use this to show indirect trapping of different types of upconverting particles and cells, and also show that we can approach a trap stiffness of 40 fN μm(−1) indicating a weak confinement regime without relying on feedback. |
format | Online Article Text |
id | pubmed-7613615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
record_format | MEDLINE/PubMed |
spelling | pubmed-76136152022-09-21 A hydro-thermophoretic trap for microparticles near a gold-coated substrate† Nalupurackal, Gokul Gunaseelan, M. Roy, Srestha Lokesh, Muruga Kumar, Sumeet Vaippully, Rahul Singh, Rajesh Roy, Basudev Soft Matter Article Optical tweezers have revolutionised micromanipulation from physics and biology to material science. However, the high laser power involved in optical trapping can damage biological samples. In this context, indirect trapping of microparticles and objects using fluid flow fields has assumed great importance. It has recently been shown that cells and particles can be turned in the pitch sense by opto-plasmonic heating of a gold surface constituting one side of a sample chamber. We extend that work to place two such hotspots in close proximity to each other to form a very unique configuration of flow fields forming an effective quasi-three-dimensional ‘trap’, assisted by thermophoresis. This is effectively a harmonic trap confining particles in all three dimensions without relying on other factors to confine the particles close to the surface. We use this to show indirect trapping of different types of upconverting particles and cells, and also show that we can approach a trap stiffness of 40 fN μm(−1) indicating a weak confinement regime without relying on feedback. 2022-08-30 2022-08-30 /pmc/articles/PMC7613615/ /pubmed/36040245 http://dx.doi.org/10.1039/d2sm00627h Text en https://creativecommons.org/licenses/by-nc/3.0/This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence (https://creativecommons.org/licenses/by-nc/3.0/) . |
spellingShingle | Article Nalupurackal, Gokul Gunaseelan, M. Roy, Srestha Lokesh, Muruga Kumar, Sumeet Vaippully, Rahul Singh, Rajesh Roy, Basudev A hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
title | A hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
title_full | A hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
title_fullStr | A hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
title_full_unstemmed | A hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
title_short | A hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
title_sort | hydro-thermophoretic trap for microparticles near a gold-coated substrate† |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613615/ https://www.ncbi.nlm.nih.gov/pubmed/36040245 http://dx.doi.org/10.1039/d2sm00627h |
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