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T cell receptor variable β20-1 harbors a nucleotide binding pocket in the CDR2β loop

Novel aspects of T cells containing TCRVβ20-1 are numerous, ranging from pathogen specific reactivity to specific tissue homing, or possible T cell subsets. Recently, it was demonstrated that TCR itself could become reactive by binding to small molecules free of the pHLA interface. Our work here was...

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Detalles Bibliográficos
Autores principales: Watkins, Stephan, Pichler, Werner J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613644/
https://www.ncbi.nlm.nih.gov/pubmed/36172593
http://dx.doi.org/10.4236/oji.2013.33021