The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein

Co-translational folding is crucial to ensure the production of biologically active proteins. The ribosome can alter the folding pathways of nascent polypeptide chains, yet a structural understanding remains largely inaccessible experimentally. We have developed site-specific labelling of nascent ch...

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Detalles Bibliográficos
Autores principales: Chan, Sammy H. S., Włodarski, Tomasz, Streit, Julian O., Cassaignau, Anaïs M. E., Woodburn, Lauren F., Ahn, Minkoo, Freiherr von Sass, Georg Johannes, Waudby, Christopher A., Budisa, Nediljko, Cabrita, Lisa D., Christodoulou, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613651/
https://www.ncbi.nlm.nih.gov/pubmed/35927328
http://dx.doi.org/10.1038/s41557-022-01004-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613651/
https://www.ncbi.nlm.nih.gov/pubmed/35927328
http://dx.doi.org/10.1038/s41557-022-01004-0

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