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Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension
Arteries grow and remodel in response to mechanical stimuli. Hypertension, for example, results in arterial wall thickening. Cell-cell Notch signaling between vascular smooth muscle cells (VSMCs) is known to be involved in this process, but the underlying mechanisms are still unclear. Here, we inves...
Autores principales: | van Asten, Jordy G.M., Ristori, Tommaso, Nolan, David R., Lally, Caitríona, Baaijens, Frank P.T., Sahlgren, Cecilia M., Loerakker, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613661/ https://www.ncbi.nlm.nih.gov/pubmed/35839633 http://dx.doi.org/10.1016/j.jmbbm.2022.105325 |
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