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Short, Divergent, and Enantioselective Total Synthesis of Bioactive ent-Pimaranes
[Image: see text] We present the first total synthesis of eight ent-pimaranes via a short and enantioselective route (11–16 steps). Key features of the divergent synthesis are a Sharpless asymmetric dihydroxylation, a Brønsted acid catalyzed cationic bicyclization, and a mild Rh-catalyzed arene hydr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613685/ https://www.ncbi.nlm.nih.gov/pubmed/36170466 http://dx.doi.org/10.1021/acs.orglett.2c02843 |