Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration

BACKGROUND & AIMS: In homeostasis, intestinal cell fate is controlled by balanced gradients of morphogen signaling. The bone morphogenetic protein (BMP) pathway has a physiological, prodifferentiation role, predominantly inferred through previous experimental pathway inactivation. Intestinal reg...

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Detalles Bibliográficos
Autores principales: Koppens, Martijn A. J., Davis, Hayley, Valbuena, Gabriel N., Mulholland, Eoghan J., Nasreddin, Nadia, Colombe, Mathilde, Antanaviciute, Agne, Biswas, Sujata, Friedrich, Matthias, Lee, Lennard, Wang, Lai Mun, Koelzer, Viktor H., East, James E., Simmons, Alison, Winton, Douglas J., Leedham, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613733/
https://www.ncbi.nlm.nih.gov/pubmed/33819486
http://dx.doi.org/10.1053/j.gastro.2021.03.052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613733/
https://www.ncbi.nlm.nih.gov/pubmed/33819486
http://dx.doi.org/10.1053/j.gastro.2021.03.052

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