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Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care

OBJECTIVE: To identify prognostic factors for health outcomes following an 8‐week supervised exercise therapy and education program for individuals with knee and hip osteoarthritis (OA) alone or with concomitant hypertension, heart or respiratory disease, diabetes mellitus, or depression. METHODS: W...

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Autores principales: Pihl, Kenneth, Roos, Ewa M., Taylor, Rod S., Grønne, Dorte T., Skou, Søren T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613737/
https://www.ncbi.nlm.nih.gov/pubmed/34085408
http://dx.doi.org/10.1002/acr.24722
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author Pihl, Kenneth
Roos, Ewa M.
Taylor, Rod S.
Grønne, Dorte T.
Skou, Søren T.
author_facet Pihl, Kenneth
Roos, Ewa M.
Taylor, Rod S.
Grønne, Dorte T.
Skou, Søren T.
author_sort Pihl, Kenneth
collection PubMed
description OBJECTIVE: To identify prognostic factors for health outcomes following an 8‐week supervised exercise therapy and education program for individuals with knee and hip osteoarthritis (OA) alone or with concomitant hypertension, heart or respiratory disease, diabetes mellitus, or depression. METHODS: We included individuals with knee and/or hip OA from the Good Life With OsteoArthritis in Denmark (GLA:D) program. GLA:D consists of 2 patient education sessions and 12 supervised exercise therapy sessions. Before GLA:D, participants self‐reported any comorbidities and were categorized into 8 comorbidity groups. Twenty‐one potential prognostic factors (demographic information, clinical data, and performance‐based physical function) gathered from participants and clinicians before the program were included. Outcomes were physical function using the 40‐meter Fast‐Paced Walk Test (FPWT), health‐related quality of life using the 5‐level EuroQol 5‐domain (EQ‐5D‐5L) index score, and pain intensity using a visual analog scale (VAS; range 0–100) assessed before and immediately after the GLA:D program. Within each comorbidity group, associations of prognostic factors with outcomes were estimated using multivariable linear regression. RESULTS: Data from 35,496 (40‐meter FPWT) and 37,576 (EQ‐5D‐5L and VAS) participants were included in the analyses. Clinically relevant associations were demonstrated between age, self‐efficacy, self‐rated health, and pain intensity and change in 40‐meter FPWT, EQ‐5D‐5L, or VAS scores across comorbidity groups. Furthermore, anxiety, education, physical function, and smoking were associated with outcomes among subgroups having depression or diabetes mellitus in addition to OA. CONCLUSION: Age, self‐efficacy, self‐rated health, and pain intensity may be prognostic of change in health outcomes following an 8‐week exercise therapy and patient education program for individuals with OA, irrespective of comorbidities.
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spelling pubmed-76137372022-11-01 Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care Pihl, Kenneth Roos, Ewa M. Taylor, Rod S. Grønne, Dorte T. Skou, Søren T. Arthritis Care Res (Hoboken) Osteoarthritis OBJECTIVE: To identify prognostic factors for health outcomes following an 8‐week supervised exercise therapy and education program for individuals with knee and hip osteoarthritis (OA) alone or with concomitant hypertension, heart or respiratory disease, diabetes mellitus, or depression. METHODS: We included individuals with knee and/or hip OA from the Good Life With OsteoArthritis in Denmark (GLA:D) program. GLA:D consists of 2 patient education sessions and 12 supervised exercise therapy sessions. Before GLA:D, participants self‐reported any comorbidities and were categorized into 8 comorbidity groups. Twenty‐one potential prognostic factors (demographic information, clinical data, and performance‐based physical function) gathered from participants and clinicians before the program were included. Outcomes were physical function using the 40‐meter Fast‐Paced Walk Test (FPWT), health‐related quality of life using the 5‐level EuroQol 5‐domain (EQ‐5D‐5L) index score, and pain intensity using a visual analog scale (VAS; range 0–100) assessed before and immediately after the GLA:D program. Within each comorbidity group, associations of prognostic factors with outcomes were estimated using multivariable linear regression. RESULTS: Data from 35,496 (40‐meter FPWT) and 37,576 (EQ‐5D‐5L and VAS) participants were included in the analyses. Clinically relevant associations were demonstrated between age, self‐efficacy, self‐rated health, and pain intensity and change in 40‐meter FPWT, EQ‐5D‐5L, or VAS scores across comorbidity groups. Furthermore, anxiety, education, physical function, and smoking were associated with outcomes among subgroups having depression or diabetes mellitus in addition to OA. CONCLUSION: Age, self‐efficacy, self‐rated health, and pain intensity may be prognostic of change in health outcomes following an 8‐week exercise therapy and patient education program for individuals with OA, irrespective of comorbidities. Wiley Periodicals, Inc. 2022-07-31 2022-11 /pmc/articles/PMC7613737/ /pubmed/34085408 http://dx.doi.org/10.1002/acr.24722 Text en © 2021 The Authors. Arthritis Care & Research published by Wiley Periodicals LLC on behalf of American College of Rheumatology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Osteoarthritis
Pihl, Kenneth
Roos, Ewa M.
Taylor, Rod S.
Grønne, Dorte T.
Skou, Søren T.
Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care
title Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care
title_full Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care
title_fullStr Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care
title_full_unstemmed Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care
title_short Prognostic Factors for Health Outcomes After Exercise Therapy and Education in Individuals With Knee and Hip Osteoarthritis With or Without Comorbidities: A Study of 37,576 Patients Treated in Primary Care
title_sort prognostic factors for health outcomes after exercise therapy and education in individuals with knee and hip osteoarthritis with or without comorbidities: a study of 37,576 patients treated in primary care
topic Osteoarthritis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613737/
https://www.ncbi.nlm.nih.gov/pubmed/34085408
http://dx.doi.org/10.1002/acr.24722
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