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Structures of α-synuclein filaments from human brains with Lewy pathology

Parkinson’s disease (PD) is the most common movement disorder, with resting tremor, rigidity, bradykinesia and postural instability being major symptoms (1). Neuropathologically, it is characterised by the presence of abundant filamentous inclusions of α-synuclein in the form of Lewy bodies and Lewy...

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Detalles Bibliográficos
Autores principales:	Yang, Yang, Shi, Yang, Schweighauser, Manuel, Zhang, Xianjun, Kotecha, Abhay, Murzin, Alexey G., Garringer, Holly J., Cullinane, Patrick W., Saito, Yuko, Foroud, Tatiana, Warner, Thomas T., Hasegawa, Kazuko, Vidal, Ruben, Murayama, Shigeo, Revesz, Tamas, Ghetti, Bernardino, Hasegawa, Masato, Lashley, Tammaryn, Scheres, Sjors H.W., Goedert, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613749/ https://www.ncbi.nlm.nih.gov/pubmed/36108674 http://dx.doi.org/10.1038/s41586-022-05319-3

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