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Repeated and On-Demand Intracellular Recordings of Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

Pharmaceutical compounds may have cardiotoxic properties, triggering potentially life-threatening arrhythmias. To investigate proarrhythmic effects of drugs, the patch clamp technique has been used as the gold standard for characterizing the electrophysiology of cardiomyocytes in vitro. However, the...

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Detalles Bibliográficos
Autores principales: Lee, Jihyun, Gänswein, Tobias, Ulusan, Hasan, Emmenegger, Vishalini, Saguner, Ardan M., Duru, Firat, Hierlemann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613763/
https://www.ncbi.nlm.nih.gov/pubmed/36166837
http://dx.doi.org/10.1021/acssensors.2c01678