Investigation into the Health Effects of Reduced Chymase Function Using Predicted Loss-of-Function Mutations in CMA1

Tissue remodelling and fibrosis which occur in response to injury play a central role in the development of many diseases. Chymase is a key enzyme believed to mediate these pathological processes. As such, chymase inhibitors have been under active development for the treatment of a number of conditi...

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Detalles Bibliográficos
Autores principales: Fairhurst-Hunter, Zammy, Walters, Robin G., Zink, Alexander, Lin, Kuang, Guo, Yu, Yu, Canqing, Lv, Jun, Li, Liming, Freitag, Daniel F., Chen, Zhengming, Millwood, Iona Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613892/
https://www.ncbi.nlm.nih.gov/pubmed/35513594
http://dx.doi.org/10.1007/s12265-022-10261-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613892/
https://www.ncbi.nlm.nih.gov/pubmed/35513594
http://dx.doi.org/10.1007/s12265-022-10261-w

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