Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor blockade

Non-human animal studies outline precise mechanisms of central mu-opioid regulation of pain, stress, affiliation and reward processing. In humans, pharmacological blockade with non-selective opioid antagonists such as naloxone and naltrexone is typically used to assess involvement of the mu-opioid s...

Descripción completa

Detalles Bibliográficos
Autores principales: Trøstheim, Martin, Eikemo, Marie, Haaker, Jan, Frost, J. James, Leknes, Siri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613944/
https://www.ncbi.nlm.nih.gov/pubmed/35978096
http://dx.doi.org/10.1038/s41386-022-01416-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613944/
https://www.ncbi.nlm.nih.gov/pubmed/35978096
http://dx.doi.org/10.1038/s41386-022-01416-z

Ejemplares similares