On-demand cell-autonomous gene therapy for brain circuit disorders

Several neurodevelopmental and neuropsychiatric disorders are characterized by intermittent episodes of pathological activity. Although genetic therapies offer the ability to modulate neuronal excitability, a limiting factor is that they do not discriminate between neurons involved in circuit pathol...

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Detalles Bibliográficos
Autores principales: Qiu, Yichen, O’Neill, Nathanael, Maffei, Benito, Zourray, Clara, Almacellas-Barbanoj, Amanda, Carpenter, Jenna C., Jones, Steffan P., Leite, Marco, Turner, Thomas J., Moreira, Francisco C., Snowball, Albert, Shekh-Ahmad, Tawfeeq, Magloire, Vincent, Barral, Serena, Kurian, Manju A., Walker, Matthew C., Schorge, Stephanie, Kullmann, Dimitri M., Lignani, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613996/
https://www.ncbi.nlm.nih.gov/pubmed/36378958
http://dx.doi.org/10.1126/science.abq6656

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