Development of selective inhibitors of phosphatidylinositol 3-kinase C2α

Phosphatidylinositol 3-kinase type 2α (PI3KC2α) and related class II PI3K isoforms are of increasing biomedical interest because of their crucial roles in endocytic membrane dynamics, cell division and signaling, angiogenesis, and platelet morphology and function. Herein we report the development an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo, Wen-Ting, Belabed, Hassane, Kücükdisli, Murat, Metag, Juliane, Roske, Yvette, Prokofeva, Polina, Ohashi, Yohei, Horatscheck, André, Cirillo, Davide, Krauss, Michael, Schmied, Christopher, Neuenschwander, Martin, von Kries, Jens Peter, Médard, Guillaume, Kuster, Bernhard, Perisic, Olga, Williams, Roger L., Daumke, Oliver, Payrastre, Bernard, Severin, Sonia, Nazaré, Marc, Haucke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613998/
https://www.ncbi.nlm.nih.gov/pubmed/36109648
http://dx.doi.org/10.1038/s41589-022-01118-z

Ejemplares similares

Ejemplares similares