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Nur77-Tempo mice reveal T cell steady state antigen recognition
In lymphocytes, Nr4a gene expression is specifically regulated by antigen receptor signalling, making them ideal targets for use as distal T cell receptor (TCR) reporters. Nr4a3-Timer of cell kinetics and activity (Tocky) mice are a ground-breaking tool to report TCR-driven Nr4a3 expression using Fl...
Autores principales: | Elliot, Thomas A. E., Jennings, Emma K., Lecky, David A. J., Rouvray, Sophie, Mackie, Gillian M., Scarfe, Lisa, Sheriff, Lozan, Ono, Masahiro, Maslowski, Kendle M., Bending, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614040/ https://www.ncbi.nlm.nih.gov/pubmed/36704407 http://dx.doi.org/10.1093/discim/kyac009 |
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