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Acute BAF perturbation causes immediate changes in chromatin accessibility

Cancer-associated loss-of-function mutations in genes coding for subunits of the BRG1/BRM associated factor (BAF) chromatin remodeling complexes(1–8) often cause drastic chromatin accessibility changes, especially in important regulatory regions(9–19). However, it remains unknown how these changes a...

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Detalles Bibliográficos
Autores principales: Schick, Sandra, Grosche, Sarah, Kohl, Katharina Eva, Drpic, Danica, Jaeger, Martin G., Marella, Nara C., Imrichova, Hana, Lin, Jung-Ming G., Hofstätter, Gerald, Schuster, Michael, Rendeiro, André F., Koren, Anna, Petronczki, Mark, Bock, Christoph, Müller, André C., Winter, Georg E., Kubicek, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614082/
https://www.ncbi.nlm.nih.gov/pubmed/33558760
http://dx.doi.org/10.1038/s41588-021-00777-3