Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro

Circular peptides are attractive lead compounds for drug development; this study investigates the immunomodulatory effects of defined root powder extracts and isolated peptides (called cyclotides) from Carapichea ipecacuanha (Brot.) L. Andersson (‘ipecac’). Changes in the viability, proliferation an...

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Detalles Bibliográficos
Autores principales: Falanga, Chiara Madlen, Steinborn, Carmen, Muratspahić, Edin, Zimmermann-Klemd, Amy Marisa, Winker, Moritz, Krenn, Liselotte, Huber, Roman, Gruber, Christian W., Gründemann, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614192/
https://www.ncbi.nlm.nih.gov/pubmed/35653889
http://dx.doi.org/10.1016/j.biopha.2022.113120

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