Cargando…

Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4

Myo-inositol tris/tetrakisphosphate kinases (ITPKs) catalyze diverse phosphotransfer reactions with myo-inositol phosphate and myo-inositol pyrophosphate substrates. However, the lack of structures of nucleotide-coordinated plant ITPKs thwarts a rational understanding of phosphotransfer reactions of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Whitfield, Hayley L., He, Sining, Gu, Yinghong, Sprigg, Colleen, Kuo, Hui-Fen, Chiou, Tzyy-Jen, Riley, Andrew M., Potter, Barry V.L., Hemmings, Andrew M., Brearley, Charles A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2023
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614388/ https://www.ncbi.nlm.nih.gov/pubmed/36896917 http://dx.doi.org/10.1042/BCJ20220579

Ejemplares similares

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels
por: Whitfield, Hayley, et al.
Publicado: (2020)

ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism
por: Desfougères, Yann, et al.
Publicado: (2019)

ITPK1 Regulates Jasmonate-Controlled Root Development in Arabidopsis thaliana
por: Pullagurla, Naga Jyothi, et al.
Publicado: (2023)

ITPK1 is an InsP(6)/ADP phosphotransferase that controls phosphate signaling in Arabidopsis
por: Riemer, Esther, et al.
Publicado: (2021)

Structural and functional analysis of cystatin E reveals enzymologically relevant dimer and amyloid fibril states
por: Dall, Elfriede, et al.
Publicado: (2018)

The Maternal ITPK1 Gene Polymorphism Is Associated with Neural Tube Defects in a High-Risk Chinese Population
por: Guan, Zhen, et al.
Publicado: (2014)

Gene editing of three BnITPK genes in tetraploid oilseed rape leads to significant reduction of phytic acid in seeds
por: Sashidhar, Niharika, et al.
Publicado: (2020)

Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism
por: Acquistapace, Isabella M., et al.
Publicado: (2020)

Roles of Phosphate Recognition in Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase (IPK1) Substrate Binding and Activation
por: Gosein, Varin, et al.
Publicado: (2013)

Pre-steady-state Kinetic Analysis of a Family D DNA Polymerase from Thermococcus sp. 9°N Reveals Mechanisms for Archaeal Genomic Replication and Maintenance
por: Schermerhorn, Kelly M., et al.
Publicado: (2015)

The Roles of Family B and D DNA Polymerases in Thermococcus Species 9°N Okazaki Fragment Maturation
por: Greenough, Lucia, et al.
Publicado: (2015)

Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria
por: Bell, Andrew, et al.
Publicado: (2020)

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches
por: Jeffreys, Laura N., et al.
Publicado: (2020)

Phytase dose-dependent response of kidney inositol phosphate levels in poultry
por: Sprigg, Colleen, et al.
Publicado: (2022)

The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN
por: Day, Martin A., et al.
Publicado: (2021)

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleT(JE)
por: Matthews, Sarah, et al.
Publicado: (2017)

Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism
por: Gunawardane, Ruwanthi N., et al.
Publicado: (2016)

Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin
por: Helmich, Kate E., et al.
Publicado: (2016)

Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1
por: Chenge, Jude T., et al.
Publicado: (2017)

Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody
por: Kenniston, Jon A., et al.
Publicado: (2014)

Biochemical Evidence for a Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor in the Olfactory System of Atlantic Salmon (Salmo salar)
por: Pang, Jiongdong, et al.
Publicado: (2013)

Investigating the reaction and substrate preference of indole-3-acetaldehyde dehydrogenase from the plant pathogen Pseudomonas syringae PtoDC3000
por: Zhang, Kaleena, et al.
Publicado: (2020)

Structure and Mechanism of Human UDP-glucose 6-Dehydrogenase
por: Egger, Sigrid, et al.
Publicado: (2011)

Comparative Kinetic and Functional Characterization of the Motor Domains of Human Nonmuscle Myosin-2C Isoforms
por: Heissler, Sarah M., et al.
Publicado: (2011)

Regulation of Response Regulator Autophosphorylation through Interdomain Contacts
por: Barbieri, Christopher M., et al.
Publicado: (2010)

Characterization of the Elongation Complex of Dengue Virus RNA Polymerase: ASSEMBLY, KINETICS OF NUCLEOTIDE INCORPORATION, AND FIDELITY
por: Jin, Zhinan, et al.
Publicado: (2011)

Molecular Characterization of a Novel Geranylgeranyl Pyrophosphate Synthase from Plasmodium Parasites
por: Artz, Jennifer D., et al.
Publicado: (2011)

The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-like Inhibitor: A REFINED MECHANISM OF SERINE PROTEASE ACTION
por: Wahlgren, Weixiao Yuan, et al.
Publicado: (2011)

Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation
por: Singleton, Rachelle S., et al.
Publicado: (2011)

Structure and Activity of Paenibacillus polymyxa Xyloglucanase from Glycoside Hydrolase Family 44
por: Ariza, Antonio, et al.
Publicado: (2011)

Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex
por: Vorontsov, Ivan I., et al.
Publicado: (2011)

NrdH-Redoxin Protein Mediates High Enzyme Activity in Manganese-reconstituted Ribonucleotide Reductase from Bacillus anthracis
por: Crona, Mikael, et al.
Publicado: (2011)

Purification and Identification of Activating Enzymes of CS-0777, a Selective Sphingosine 1-Phosphate Receptor 1 Modulator, in Erythrocytes
por: Yonesu, Kiyoaki, et al.
Publicado: (2011)

Two Drosophila Myosin Transducer Mutants with Distinct Cardiomyopathies Have Divergent ADP and Actin Affinities
por: Bloemink, Marieke J., et al.
Publicado: (2011)

Comparative Analysis of Histophilus somni Immunoglobulin-binding Protein A (IbpA) with Other Fic Domain-containing Enzymes Reveals Differences in Substrate and Nucleotide Specificities
por: Mattoo, Seema, et al.
Publicado: (2011)

Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme
por: Walsh, John G., et al.
Publicado: (2011)

Mining Endonuclease Cleavage Determinants in Genomic Sequence Data
por: Szeto, Mindy D., et al.
Publicado: (2011)

Human Carboxymethylenebutenolidase as a Bioactivating Hydrolase of Olmesartan Medoxomil in Liver and Intestine
por: Ishizuka, Tomoko, et al.
Publicado: (2010)

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity
por: Schwendener, Sybille, et al.
Publicado: (2010)

Dynamic Mechanism of Proton Transfer in Mannitol 2-Dehydrogenase from Pseudomonas fluorescens: MOBILE GLU(292) CONTROLS PROTON RELAY THROUGH A WATER CHANNEL THAT CONNECTS THE ACTIVE SITE WITH BULK SOLVENT
por: Klimacek, Mario, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7bhe6mjvvpg6d2rs95u3un32ec