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Activation of human CD8+ T-cells with nitroso dapsone-modified HLA-B*13:01-binding peptides()
Previous studies have shown that cysteine-reactive drug metabolites bind covalently with protein to activate patient T-cells. However, the nature of the antigenic determinants that interact with HLA, and whether T-cell stimulatory peptides contain the bound drug metabolite has not been defined. Sinc...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614401/ https://www.ncbi.nlm.nih.gov/pubmed/36881872 http://dx.doi.org/10.4049/jimmunol.2200531 |