Activation of human CD8+ T-cells with nitroso dapsone-modified HLA-B*13:01-binding peptides()

Previous studies have shown that cysteine-reactive drug metabolites bind covalently with protein to activate patient T-cells. However, the nature of the antigenic determinants that interact with HLA, and whether T-cell stimulatory peptides contain the bound drug metabolite has not been defined. Sinc...

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Detalles Bibliográficos
Autores principales: Almutairi, Mubarak, Lister, Adam, Zhao, Qing, Line, James, Adair, Kareena, Tailor, Arun, Waddington, James, Clarke, Elsie, Gardner, Joshua, Thomson, Paul, Harper, Nicolas, Sun, Yonghu, Sun, Lele, Ostrov, David A., Liu, Hong, MacEwan, David J., Pirmohamed, Munir, Meng, Xiaoli, Zhang, Furen, Naisbitt, Dean J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614401/
https://www.ncbi.nlm.nih.gov/pubmed/36881872
http://dx.doi.org/10.4049/jimmunol.2200531

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