Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary necrosis and autoimmune activation by intracellular self antigens. We show by multiple...

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Detalles Bibliográficos
Autores principales: Grootveld, Abigail K., Kyaw, Wunna, Panova, Veera, Lau, Angelica W.Y., Ashwin, Emily, Seuzaret, Guillaume, Dhenni, Rama, Bhattacharyya, Nayan Deger, Khoo, Weng Hua, Biro, Maté, Mitra, Tanmay, Meyer-Hermann, Michael, Bertolino, Patrick, Tanaka, Masato, Hume, David A., Croucher, Peter I., Brink, Robert, Nguyen, Akira, Bannard, Oliver, Phan, Tri Giang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614509/
https://www.ncbi.nlm.nih.gov/pubmed/36868219
http://dx.doi.org/10.1016/j.cell.2023.02.004

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