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IL-18 Binding Protein–Producing Cells Attenuate Anemia in Murine Macrophage Activation Syndrome

IL-18 is a pleiotropic immunoregulatory cytokine of the IL-1 family. IL-18 has been identified as a potent IFN-γ inducer in synergy with IL-12 and IL-15 and thus as a powerful Th1 cell–polarizing cytokine. IL-18 activity is regulated by its naturally occurring soluble inhibitor IL-18 binding protein...

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Detalles Bibliográficos
Autores principales:	Harel, Mathilde, Fauteux-Daniel, Sébastien, Rodriguez, Emiliana, Palmer, Gaby, Gabay, Cem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2023
Materias:	Innate Immunity and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614543/ https://www.ncbi.nlm.nih.gov/pubmed/37074208 http://dx.doi.org/10.4049/jimmunol.2300065

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