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Data-driven design of orthogonal protein-protein interactions
Engineering protein-protein interactions to generate new functions presents a challenge with great potential for many applications, ranging from therapeutics to synthetic biology. To avoid unwanted cross-talk with preexisting protein interaction networks in a cell, the specificity and selectivity of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614567/ https://www.ncbi.nlm.nih.gov/pubmed/36853962 http://dx.doi.org/10.1126/scisignal.abm4484 |