Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development

Childhood psychiatric symptoms are often diffuse but can coalesce into discrete mental illnesses during late adolescence. We leveraged polygenic scores (PGSs) to parse genomic risk for childhood symptoms and to uncover related neurodevelopmental mechanisms with transcriptomic and neuroimaging data....

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Detalles Bibliográficos
Autores principales: Hughes, Dylan E., Kunitoki, Keiko, Elyounssi, Safia, Luo, Mannan, Bazer, Oren M., Hopkinson, Casey E., Dowling, Kevin F., Doyle, Alysa E., Dunn, Erin C., Eryilmaz, Hamdi, Gilman, Jodi M., Holt, Daphne J., Valera, Eve M., Smoller, Jordan W., Cecil, Charlotte A. M., Tiemeier, Henning, Lee, Phil H., Roffman, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614744/
https://www.ncbi.nlm.nih.gov/pubmed/37202553
http://dx.doi.org/10.1038/s41593-023-01321-8

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