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Angiotensin type 2 receptor antagonism as a new target to manage gout

BACKGROUND: There is a growing search for therapeutic targets in the treatment of gout. The present study aimed to evaluate the analgesic and anti-inflammatory potential of angiotensin type 2 receptor (AT(2)R) antagonism in an acute gout attack mouse model. METHODS: Male wild type (WT) C57BL/6 mice...

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Detalles Bibliográficos
Autores principales: Vieira, Thiago Neves, Lopes Saraiva, André L., Guimarães, Rafaela Mano, Luiz, João Paulo Mesquita, Pinto, Larissa Garcia, de Melo Rodrigues Ávila, Veridiana, Goulart, Luiz Ricardo, Cunha-Junior, Jair Pereira, McNaughton, Peter Anthony, Cunha, Thiago Mattar, Ferreira, Juliano, Silva, Cassia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614762/
https://www.ncbi.nlm.nih.gov/pubmed/36173505
http://dx.doi.org/10.1007/s10787-022-01076-x