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T-bet and RORα control lymph node formation by regulating embryonic innate lymphoid cell differentiation

The generation of lymphoid tissues during embryogenesis relies on group 3 innate lymphoid cells (ILC3) displaying lymphoid tissue inducer (LTi) activity and expressing the master transcription factor RORγt. Accordingly, RORγt-deficient mice lack ILC3 and lymphoid structures, including lymph nodes (L...

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Detalles Bibliográficos
Autores principales:	Stehle, Christina, Rückert, Timo, Fiancette, Rémi, Gajdasik, Dominika W., Willis, Claire, Ulbricht, Carolin, Durek, Pawel, Mashreghi, Mir-Farzin, Finke, Daniela, Hauser, Anja Erika, Withers, David R., Chang, Hyun-Dong, Zimmermann, Jakob, Romagnani, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614953/ https://www.ncbi.nlm.nih.gov/pubmed/34556887 http://dx.doi.org/10.1038/s41590-021-01029-6

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