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Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy

The human uterine transplant (UTx) is being developed as a procedure to alleviate absolute uterine factor infertility (AUFI). In light of recent UTx advances in India, I suggest that key ethical concerns would emerge if this procedure were to become established as part of India’s liberalised assiste...

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Autor principal: Barn, Gulzaar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614995/
https://www.ncbi.nlm.nih.gov/pubmed/32627314
http://dx.doi.org/10.1111/dewb.12274
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author Barn, Gulzaar
author_facet Barn, Gulzaar
author_sort Barn, Gulzaar
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description The human uterine transplant (UTx) is being developed as a procedure to alleviate absolute uterine factor infertility (AUFI). In light of recent UTx advances in India, I suggest that key ethical concerns would emerge if this procedure were to become established as part of India’s liberalised assisted reproduction industry. On evidence-based projections, UTx would be likely to harm vulnerable populations in two key ways. Firstly, I suggest that a commercial model for uteri procurement is primed to develop due to various structural factors that facilitated the boom in commercial surrogacy remaining in place, despite commercial surrogacy having been outlawed. I outline ways in which Indian commercial surrogacy arrangements exhibited exploitation and suggest that a commercial UTx model would be similarly exploitative, with many background features of exploitative surrogacy remaining constant. The second way in which the development of UTx in India might pose harm is through the difficulty in obtaining proper informed consent, even under altruistic arrangements. I argue that structural factors, including a cultural deference to doctors, lack of medical understanding displayed by vulnerable populations, and a privatised healthcare system with little regulatory oversight, would render it difficult to obtain proper informed consent from living donors. Further, factors peculiar to UTx, such as its experimental nature, and the unknown and novel risks and harms it poses, heighten this difficulty. Accordingly, UTx in India would be unlikely to meet the Montreal criteria for the ethical feasibility of uterine transplantation and should thus raise ethical alarm.
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spelling pubmed-76149952023-08-31 Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy Barn, Gulzaar Dev World Bioeth Article The human uterine transplant (UTx) is being developed as a procedure to alleviate absolute uterine factor infertility (AUFI). In light of recent UTx advances in India, I suggest that key ethical concerns would emerge if this procedure were to become established as part of India’s liberalised assisted reproduction industry. On evidence-based projections, UTx would be likely to harm vulnerable populations in two key ways. Firstly, I suggest that a commercial model for uteri procurement is primed to develop due to various structural factors that facilitated the boom in commercial surrogacy remaining in place, despite commercial surrogacy having been outlawed. I outline ways in which Indian commercial surrogacy arrangements exhibited exploitation and suggest that a commercial UTx model would be similarly exploitative, with many background features of exploitative surrogacy remaining constant. The second way in which the development of UTx in India might pose harm is through the difficulty in obtaining proper informed consent, even under altruistic arrangements. I argue that structural factors, including a cultural deference to doctors, lack of medical understanding displayed by vulnerable populations, and a privatised healthcare system with little regulatory oversight, would render it difficult to obtain proper informed consent from living donors. Further, factors peculiar to UTx, such as its experimental nature, and the unknown and novel risks and harms it poses, heighten this difficulty. Accordingly, UTx in India would be unlikely to meet the Montreal criteria for the ethical feasibility of uterine transplantation and should thus raise ethical alarm. 2021-09-01 2020-07-06 /pmc/articles/PMC7614995/ /pubmed/32627314 http://dx.doi.org/10.1111/dewb.12274 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the Creative Commons Attribution (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Barn, Gulzaar
Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy
title Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy
title_full Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy
title_fullStr Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy
title_full_unstemmed Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy
title_short Uterus Transplants and the Potential for Harm: Lessons From Commercial Surrogacy
title_sort uterus transplants and the potential for harm: lessons from commercial surrogacy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614995/
https://www.ncbi.nlm.nih.gov/pubmed/32627314
http://dx.doi.org/10.1111/dewb.12274
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