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Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B cell responses: A randomised, controlled, human infection trial

BACKGROUND: Pharyngeal colonisation by the harmless commensal Neisseria lactamica (Nlac) inhibits Neisseria meningitidis (Nmen) colonisation and has an inverse epidemiological association with meningococcal disease. The mechanisms underpinning this relationship remain unexplained, but could be due t...

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Detalles Bibliográficos
Autores principales: Dale, Adam P., Theodosiou, Anastasia A., Gbesemete, Diane F., Guy, Jonathan M., Jones, Eleanor F., Hill, Alison R., Ibrahim, Muktar M., de Graaf, Hans, Ahmed, Muhammad, Faust, Saul N., Gorringe, Andrew R., Polak, Marta E., Laver, Jay R., Read, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615047/
https://www.ncbi.nlm.nih.gov/pubmed/36462524
http://dx.doi.org/10.1016/S2666-5247(22)00283-X