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Cre toxicity in mouse models of cardiovascular physiology and disease

The Cre-LoxP system provides a widely used method for studying gene requirements in the mouse as the main mammalian genetic model organism. To define the molecular and cellular mechanisms that underlie cardiovascular development, function and disease, various mouse strains have been engineered that...

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Detalles Bibliográficos
Autores principales: Rashbrook, Victoria S., Brash, James T., Ruhrberg, Christiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615056/
https://www.ncbi.nlm.nih.gov/pubmed/37692772
http://dx.doi.org/10.1038/s44161-022-00125-6