Rare Variants in the MECP2 Gene in Girls with Central Precocious Puberty

BACKGROUND: Identification of genetic causes of central precocious puberty (CPP) has revealed epigenetic mechanisms as regulators of human pubertal timing. Methyl-CpG-binding protein 2 (MECP2), an X-linked gene, encodes a chromatin-associated protein with a role in gene transcription. MECP2 loss-of-...

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Detalles Bibliográficos
Autores principales: Canton, Ana P. M., Tinano, Flávia R., Guasti, Leonardo, Montenegro, Luciana R., Ryan, Fiona, Shears, Deborah, de Melo, Maria Edna, Gomes, Larissa G., Piana, Mariana P., Brauner, Raja, Aguilar, Rafael E., Escribano-Munôz, Arancha, Paganoni, Alyssa, Read, Jordan, Korbonits, Márta, Seraphim, Carlos E., Costa, Silvia S., Krepischi, Ana Cristina, Jorge, Alexander A. L., David, Alessia, Kaisinger, Lena R., Ong, Ken K., Perry, John R. B., Abreu, Ana Paula, Kaiser, Ursula B., Argente, Jesús, Mendonca, Berenice B., Brito, Vinicius N., Howard, Sasha R., Latronico, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615084/
https://www.ncbi.nlm.nih.gov/pubmed/37385287
http://dx.doi.org/10.1016/S2213-8587(23)00131-6

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