Incongruence between transcriptional and vascular pathophysiological cell states

The Notch pathway is a major regulator of endothelial transcriptional specification. Targeting the Notch receptors or Delta-like ligand 4 (Dll4) dysregulates angiogenesis. Here, by analyzing single and compound genetic mutants for all Notch signaling members, we find significant differences in the w...

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Detalles Bibliográficos
Autores principales: Fernández-Chacón, Macarena, Mühleder, Severin, Regano, Alvaro, Garcia-Ortega, Lourdes, Rocha, Susana F., Torroja, Carlos, Sanchez-Muñoz, Maria S., Lytvyn, Mariya, Casquero-Garcia, Verónica, De Andrés-Laguillo, Macarena, Muhl, Lars, Orlich, Michael M., Gaengel, Konstantin, Camafeita, Emilio, Vázquez, Jesús, Benguría, Alberto, Iruela-Arispe, M. Luisa, Dopazo, Ana, Sánchez-Cabo, Fátima, Carter, Hannah, Benedito, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615119/
https://www.ncbi.nlm.nih.gov/pubmed/37745941
http://dx.doi.org/10.1038/s44161-023-00272-4

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