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Altered basal lipid metabolism underlies the functional impairment of naive CD8(+) T cells in elderly humans

Aging is associated with functional deficits in the naive T cell compartment, which compromise the generation of de novo immune responses against previously unencountered antigens. The mechanisms that underlie this phenomenon have nonetheless remained unclear. We found that naive CD8(+) T cells in e...

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Detalles Bibliográficos
Autores principales:	Nicoli, Francesco, Cabral-Piccin, Mariela P., Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J., Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A., Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo, Appay, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615155/ https://www.ncbi.nlm.nih.gov/pubmed/35031578 http://dx.doi.org/10.4049/jimmunol.2100194

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