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Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors

Membrane proteins are challenging to analyze by native mass spectrometry (MS) as their hydrophobic nature typically requires detergent micelles that are removed prior to analysis via collisional activation. There is however a practical limit to the amount of energy which can be applied, which often...

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Detalles Bibliográficos
Autores principales:	Lutomski, Corinne A., El-Baba, Tarick J., Hinkle, Joshua D., Liko, Idlir, Bennett, Jack L., Kalmankar, Neha V., Dolan, Andrew, Kirschbaum, Carla, Greis, Kim, Urner, Leonhard H., Kapoor, Parth, Yen, Hsin-Yung, Pagel, Kevin, Mullen, Christopher, Syka, John E. P., Robinson, Carol V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615181/ https://www.ncbi.nlm.nih.gov/pubmed/37329506 http://dx.doi.org/10.1002/anie.202305694

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