Cargando…

Dimethyl sulfoxide’s impact on epileptiform activity in a mouse model of chronic temporal lobe epilepsy

In the quest for novel treatments for patients with drug-resistant seizures, poor water solubility of potential drug candidates is a frequent obstacle. Literature indicated that the highly efficient solvent dimethyl sulfoxide (DMSO) may have a confounding influence in epilepsy research, reporting bo...

Descripción completa

Detalles Bibliográficos
Autores principales: Widmann, Melanie, Lieb, Andreas, Mutti, Anna, Schwarzer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615238/
https://www.ncbi.nlm.nih.gov/pubmed/37797423
http://dx.doi.org/10.1016/j.eplepsyres.2023.107235