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Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNA(Pyl) pairs

Mutually orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs provide a foundation for encoding non-canonical amino acids (ncAAs) into proteins, and encoded non-canonical polymer and macrocycle synthesis. Here we discover quintuply orthogonal pyrrolysyl-tRNA synthetase (PylRS)/ tRNA(Pyl) pairs. We...

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Detalles Bibliográficos
Autores principales:	Beattie, Adam T., Dunkelmann, Daniel L., Chin, Jason W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615293/ https://www.ncbi.nlm.nih.gov/pubmed/37322102 http://dx.doi.org/10.1038/s41557-023-01232-y

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