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Appraising the causal role of risk factors in coronary artery disease and stroke: A systematic review of Mendelian Randomization studies

BACKGROUND: Mendelian randomization (MR) offers a powerful approach to study potential causal associations between exposures and health outcomes, by using genetic variants associated with an exposure as instrumental variables. In this systematic review, we aimed to summarize previous MR studies and...

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Detalles Bibliográficos
Autores principales: Georgiou, Andrea N, Zagkos, Loukas, Markozannes, Georgios, Chalitsios, Christos V., Asimakopoulos, Alexandros Georgios, Xu, Wei, Wang, Lijuan, Mesa-Eguiagaray, Ines, Zhou, Xuan, Loizidou, Eleni M, Kretsavos, Nikolaos, Theodoratou, Evropi, Gill, Dipender, Burgess, Stephen, Evangelou, Evangelos, Tsilidis, Konstantinos K, Tzoulaki, Ioanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615320/
https://www.ncbi.nlm.nih.gov/pubmed/37804188
http://dx.doi.org/10.1161/JAHA.122.029040