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Increased hippocampal TrkA expression ameliorates cranial radiation-induced neurogenesis impairment and cognitive deficit via PI3K/AKT signaling

Cognitive deficit is one of the most serious complications of cranial radiotherapy of head and neck cancers. However, the underlying mechanism of this cognitive impairment remains unclear. In the present study, the role of tropomyosin receptor kinase A (TrkA) and its ligand neurotrophin nerve growth...

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Detalles Bibliográficos
Autores principales:	Ji, Shengjun, Wu, Haohao, Ding, Xin, Chen, Qingqing, Jin, Xing, Yu, Jinming, Yang, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640353/ https://www.ncbi.nlm.nih.gov/pubmed/33125501 http://dx.doi.org/10.3892/or.2020.7782

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