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HFD and HFD-provoked hepatic hypoxia act as reciprocal causation for NAFLD via HIF-independent signaling
BACKGROUND: The occurrence of non-alcoholic fatty liver disease (NAFLD) is found to be higher in patients with obstructive sleep apnea (OSA), which is characterized by intermittent hypoxia. Activation of hypoxia-inducible factors has been shown in the development and progression of NAFLD, implying a...
Autores principales: | Zhang, Xiaofang, Huang, Caoxin, Li, Xuejun, Shangguan, Zhaoshui, Wei, Wenjing, Liu, Suhuan, Yang, Shuyu, Liu, Yijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640429/ https://www.ncbi.nlm.nih.gov/pubmed/33143650 http://dx.doi.org/10.1186/s12876-020-01515-5 |
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