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Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention

OBJECTIVES: This study aimed to assess the effect of the admission time (on-hours versus off-hours) on in-hospital mortality in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI) in a region without STEMI network. METHODS: We analy...

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Autores principales: Javanshir, Elnaz, Ramandi, Elham Darzi, Ghaffari, Samad, Nasiri, Babak, Bodagh, Haleh, Davarmoin, Ghiti, Aslanabadi, Naser, Separham, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Saudi Heart Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640545/
https://www.ncbi.nlm.nih.gov/pubmed/33154924
http://dx.doi.org/10.37616/2212-5043.1059
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author Javanshir, Elnaz
Ramandi, Elham Darzi
Ghaffari, Samad
Nasiri, Babak
Bodagh, Haleh
Davarmoin, Ghiti
Aslanabadi, Naser
Separham, Ahmad
author_facet Javanshir, Elnaz
Ramandi, Elham Darzi
Ghaffari, Samad
Nasiri, Babak
Bodagh, Haleh
Davarmoin, Ghiti
Aslanabadi, Naser
Separham, Ahmad
author_sort Javanshir, Elnaz
collection PubMed
description OBJECTIVES: This study aimed to assess the effect of the admission time (on-hours versus off-hours) on in-hospital mortality in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI) in a region without STEMI network. METHODS: We analysed in-hospital the mortality among 300 consecutive ST-segment elevation myocardial infarction (STEMI) patients treated with PPCI between March 2012 and February 2017. Patients were divided according to admission time into on-hours admission (08:00 AM until 08:00 PM on weekdays) versus off-hours admission (08:00 PM until 08:00 AM on weekdays and 24 h on weekends and holidays). Demographic and clinical data as well as in-hospital mortality were compared between the two groups. RESULTS: One hundred and seventy eight (59.3%) patients were admitted during on-hours, and 122 (40.7%) patients were presented in off-hours. The mean door-to-balloon time was 42.3 min in the off-hours group and 34.2 min in the on-hours group with no statistically significant difference (p = 0.39). The mortality rate was 3.9% at on-hours presentation versus 4.09% in off-hours admission (p = 0.58). Multivariate logistic regression analysis showed that off-hours presentation was not associated with in-hospital mortality. [odds ratio (OR) 0.74; 95% CI, 0.21–2.61, p = 0.64]. CONCLUSION: Despite no efficient STEMI network in present study, off-hour presentation had no significant impact on in-hospital prognosis in patients with STEMI treated with PPCI. Larger studies are warranted in order to determine the prognostic role of off-hour presentation in patients with STEMI undergoing PPCI.
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spelling pubmed-76405452020-11-04 Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention Javanshir, Elnaz Ramandi, Elham Darzi Ghaffari, Samad Nasiri, Babak Bodagh, Haleh Davarmoin, Ghiti Aslanabadi, Naser Separham, Ahmad J Saudi Heart Assoc Full Length Article OBJECTIVES: This study aimed to assess the effect of the admission time (on-hours versus off-hours) on in-hospital mortality in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI) in a region without STEMI network. METHODS: We analysed in-hospital the mortality among 300 consecutive ST-segment elevation myocardial infarction (STEMI) patients treated with PPCI between March 2012 and February 2017. Patients were divided according to admission time into on-hours admission (08:00 AM until 08:00 PM on weekdays) versus off-hours admission (08:00 PM until 08:00 AM on weekdays and 24 h on weekends and holidays). Demographic and clinical data as well as in-hospital mortality were compared between the two groups. RESULTS: One hundred and seventy eight (59.3%) patients were admitted during on-hours, and 122 (40.7%) patients were presented in off-hours. The mean door-to-balloon time was 42.3 min in the off-hours group and 34.2 min in the on-hours group with no statistically significant difference (p = 0.39). The mortality rate was 3.9% at on-hours presentation versus 4.09% in off-hours admission (p = 0.58). Multivariate logistic regression analysis showed that off-hours presentation was not associated with in-hospital mortality. [odds ratio (OR) 0.74; 95% CI, 0.21–2.61, p = 0.64]. CONCLUSION: Despite no efficient STEMI network in present study, off-hour presentation had no significant impact on in-hospital prognosis in patients with STEMI treated with PPCI. Larger studies are warranted in order to determine the prognostic role of off-hour presentation in patients with STEMI undergoing PPCI. Saudi Heart Association 2020-06-04 /pmc/articles/PMC7640545/ /pubmed/33154924 http://dx.doi.org/10.37616/2212-5043.1059 Text en © 2020 Saudi Heart Association This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Full Length Article
Javanshir, Elnaz
Ramandi, Elham Darzi
Ghaffari, Samad
Nasiri, Babak
Bodagh, Haleh
Davarmoin, Ghiti
Aslanabadi, Naser
Separham, Ahmad
Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
title Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
title_full Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
title_fullStr Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
title_full_unstemmed Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
title_short Association Between Off-hour Presentations and In-hospital Mortality for Patients with Acute ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
title_sort association between off-hour presentations and in-hospital mortality for patients with acute st-elevation myocardial infarction treated with primary percutaneous coronary intervention
topic Full Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640545/
https://www.ncbi.nlm.nih.gov/pubmed/33154924
http://dx.doi.org/10.37616/2212-5043.1059
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