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Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection
Leishmania spp. infection is a global health problem affecting more than 2 million people every year with 300 million at risk worldwide. It is well established that a dominant Th1 response (IFN-γ, a hallmark Th1 cytokine) provides resistance, whereas a dominant Th2 response (IL-4, a hallmark Th2 cyt...
Autores principales: | Poudel, Barun, Yorek, Matthew S., Mazgaeen, Lalita, Brown, Scott A., Kanneganti, Thirumala-Devi, Gurung, Prajwal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640617/ https://www.ncbi.nlm.nih.gov/pubmed/32948646 http://dx.doi.org/10.4049/immunohorizons.2000076 |
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